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晏乐三


  

晏乐三,研究员,博士生导师,湖北省高层次人才(青年项目)



个人简介

    晏乐三,研究员,博士生导师。主要从事生物医用高分子材料的研究,在生物可降解高分子材料的设计与合成,高分子药物((铂类金属、蛋白,基因等)递送系统,以及位点特异性抗体-药物键合物等方向都有深入的研究。至今,在国际主流期刊上发表SCI论文60余篇。曾荣获/入选湖北省海外高层次人才计划(青年项目)、楚天学子,2020年度中/韩国生物材料协会年青年科学家奖、2022年度英国皇家化学学会Journal of Materials Chemistry B新锐科学家、2015年吉林省自然科学二等奖等。

教育经历

    2003.09-2007.07  武汉理工大学,高分子材料与工程专业,学士

    2007.09-2013.01  中国科学院长春应用化学研究所,高分子化学与物理,博士

工作经历

    2013.02-2014.03  美国约翰霍普金斯大学,生物医学工程系,博士后

    2014.04-2018.02  美国宾夕法尼亚大学,生物医学工程系,博士后

    2018.03-2019.06  美国宾夕法尼亚大学,生物医学工程系,Research Associate

    2019.09-至今     武汉理工大学,材料复合新技术国家重点实验室,研究员

研究领域

    1. 生物可降解高分子材料

    2. 纳米药物载体及靶向药物递送

    3. 纳米探针与分子成像

近期主要科研项目

    1. 国家自然科学基金青年项目,项目编号:52003211,2021-2023

    2. 湖北省自然科学基金青年项目,项目编号:2020CFB418,2020-2022

 3. 武汉理工大学海外人才引进科研启动项目,2019-2022

 4. 湖北省高层次人才青年项目,2022-2026


近期发表论文

1. Shuangyu Tian, Jinghang Li, Dongdong Wang, Yingchao Han, Honglian Dai, and Lesan Yan*, Sonodynamic-Chemotherapy Synergy with Chlorin e6-based Carrier-free Nanoparticles for Non-Small Cell Lung Cancer, Journal of Materials Chemistry B, 2024,12, 3282-3291

2. Qiang Cheng, Weixing Wang, Xianzhen Dong, Yunhui Chai, Takashi Goto, Rong Tu, Lesan Yan*, Aixi Yu*, and Honglian Dai*, An Adaptable Drug Delivery System Facilitates Peripheral Nerve Repair by Remodeling the Microenvironment, Biomacromolecules, 2024, 25 (3), 1509-1526

3. Xianzhen Dong, Hao Zhang, Ping Duan, Kun Liu, Yifeng Yu, Wenying Wei, Weixing Wang, Yuhang Liu, Qiang Cheng, Xinyue Liang, Yuanfang Huo, Lesan Yan*, Aixi Yu*, and Honglian Dai*, An injectable and adaptable hydrogen sulfide delivery system for modulating neuroregenerative microenvironment, Science Advances, 2023, 9 (51), eadi1078

4. Dongdong Wang, Mu Li, Hanning Zhang, Congshu Feng, Lili Wu, and Lesan Yan*, A Novel Redox-Sensitive Drug Delivery System Based on Trimethyl-Locked Polycarbonate, Biomacromolecules, 2023, 24(9), 4303-4315

5. Jinhai Xie, Shuangyu Tian, Hanning Zhang, Congshu Feng, Yingchao Han, Honglian Dai, and Lesan Yan*, A Novel NQO1 Enzyme-Responsive Polyurethane Nanocarrier for Redox-Triggered Intracellular Drug Release, Biomacromolecules, 2023, 24 (5), 2225-2236

6. Hanning Zhang, Shuangyu Tian, Mu Li, Jinhai Xie, HongLian Dai, Liuyong Hu, and Lesan Yan*, Novel Donor-Acceptor Conjugated Polymer-Based Nanomicelles for Photothermal Therapy in the NIR Window, Biomacromolecules, 2022, 23 (8), 3243-3256

7. Diya Shi, Congshu Feng, Jinhai Xie, Xi Zhang, HongLian Dai, and Lesan Yan*, Recent Progress of Nanomedicine on Secreted Phospholipase A2 as a Potential Therapeutic Target, Journal of Materials Chemistry B, 2022, 10, 7349-7360

8. Lesan Yan, Lijun Luo, Ahmad Amirshaghaghi, Joann Miller, Cathy Meng, Tianyan You, Theresa M Busch, Andrew Tsourkas, and Zhiliang Cheng*. Dextran-Benzoporphyrin Derivative (BPD) Coated Superparamagnetic Iron Oxide Nanoparticle (SPION) Micelles for T2-Weighted Magnetic Resonance Imaging and Photodynamic Therapy. Bioconjugate Chemistry, 2019, 30 (11), 2974-2981

9. Lesan Yan, Ahmad Amirshaghaghi, Dennis Huang, Joann Miller, Joel M. Stein, Theresa M. Busch, Zhiliang Cheng*, and Andrew Tsourkas*. Protoporphyrin IX (PpIX)-coated superparamagnetic iron oxide nanoparticle (SPION) nanoclusters for Magnetic Resonance Imaging and Photodynamic Therapy. Advanced Functional Materials. 2018, 28, 1707030.   

10. Lesan Yan, Samuel H. Crayton, Jayesh P. Thawani, Ahmad Amirshaghaghi, Andrew Tsourkas and Zhiliang Cheng*. A pH-responsive drug delivery platform based on glycol chitosan-coated liposomes. Small, 2015, 11 (37), 4870-4874.


联系方式

    电话:15972199746

    邮箱:lsyan@whut.edu.cn

    工作单位:武汉理工大学材料复合新技术国家重点实验室

    联系地址:武汉市洪山区珞狮路122号武汉理工大学马房山校区西院逸夫楼7-8


招生招聘

    课题组欢迎具备材料、化学、生物、医学和药学等专业背景的优秀本科、硕士和博士生加盟。有意者请将个人简历发送至晏老师邮箱。


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通讯地址:湖北省武汉市武昌区洪山珞狮路122号 (中国 武汉 430070)

邮编:430070

电话:027-87884448

E-mail:sklwut@whut.edu.cn